Nicotinamide riboside (NR) Increases NADP

In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. Studies in mice have shown that boosting the levels of this cell metabolite—known as NAD —can produce multiple health benefits, including resistance to weight gain, improved control of bl...

 Genetic Language is Abstract and Flexible

The awesome power that genetic engineering will one day place in our hands was foreshadowed recently by some experimenters at the University of Basel in Switzerland. Walter Gehring and his students were studying the effects of the eyeless gene in fruit flies. The gene is called eyeless because its absence causes flies to grow without eyes. The gene actually causes eyes to grow. Gehring and the students inserted the gene into various tissues of embryonic flies, and the embryos grew into flies ...

 The Universality of Analogy

This reversibility and this polyvalency endow analogy with a universal field of application. Through it, all the figures in the whole universe can be drawn together. There does exist, however, in this space, furrowed in every direction, one particularly privileged point: it is saturated with analogies (all analogies can find one of their necessary terms there), and as they pass through it, their relations may be inverted without losing any of their force. This point is man: he stands in propo...

 Extropist Philosophy

Endless eXtension - Extropists seek perpetual growth and progress in all aspects of human endeavor. We are, as a species and as a culture, never finished or in any essential way complete. Instead, we continually pursue knowledge, we constantly experiment, we forever continue to develop techniques that improve our minds, our bodies, our culture and our environment. Extropists affirm this belief and take it to its logical conclusion. We desire the technology and understanding that allows us to...

 Fireside Conversation Sparked Storytelling

Control of fire and the capacity for cooking led to major anatomical and residential changes for early humans, starting more than a million years ago. However, little is known about what transpired when the day was extended by firelight. Data from the Ju/’hoan hunter-gatherers of southern Africa show major differences between day and night talk. Day talk centered on practicalities and sanctioning gossip; firelit activities centered on conversations that evoked the imagination, helped people...